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Aspirin offers men and women different protection from heart disease

For years we have heard that daily aspirin therapy may reduce the risk of heart attacks and strokes. Now, a new study finds that our genders -- based on different metabolic responses -- may affect its potency. According to findings published in a recent Journal of the American Medical Association, aspirin therapy reduced strokes in women by 17 percent and heart attacks in men by 32 percent. The findings, analyzing data gathered from 95,456 patients from six clinical trials, show that among women, aspirin had no significant effect on the risk of a heart attack. As a result, experts say the findings indicate a need to develop a risk calculator to determine potential risk of first strokes in women. Other experts say the gender-difference findings could be questioned based on certain trial factors, such as female trial participants' age. The study also found that aspirin increases risk of major bleeding regardless of gender.

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